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FLASH GENE
Symbol GNG3 contributors: mct - updated : 09-03-2009
HGNC name guanine nucleotide binding protein (G protein), gamma 3
HGNC id 4405
Location 11q12.3      Physical location : 62.475.113 - 62.476.677
Synonym name
  • guanine nucleotide-binding protein gamma-3 subunit
  • NBP gamma-3
  • guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
  • Synonym symbol(s) GNGT3, IG, SG
    DNA
    TYPE functioning gene
    SPECIAL FEATURE head to head
    text head to head with BSCL2
    STRUCTURE 1.57 kb     3 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Map cen - D11S1765 - ADRBK1 - D11S2237E - D11S3598 - GNG3 - D11S4063 - D11S2422 - CD5 - D11S913 - qter
    Physical map
    ASRGL1 11q12.3 asparaginase like 1 SCGB1A1 11q12.2-q13.1 secretoglobin, family 1A, member 1 (uteroglobin) MGC5395 11q12.2 hypothetical protein MGC5395 EEF1G 11q13.2 eukaryotic translation elongation factor 1 gamma FLJ22347 11q12.2 hypothetical protein FLJ22347 MTA2 11q12-q13.1 metastais-associated gene family, member 2 FLJ35827 11q12.3 hypothetical protein FLJ35827 ROM1 11q13.1 retinal outer segment membrane protein 1 B3GAT3 11q12.2 beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I) G2AN 11q12.3 alpha glucosidase II alpha subunit KIAA1698 11q12.3 KIAA1698 protein MGC2477 11q12.3 hypothetical protein MGC2477 LOC51035 11q12.3 ORF LOC221091 11q12.3 similar to hypothetical protein BSCL2 11q12.q13.5 Bernardinelli-Seip congenital lipodystrophy 2 (seipin) GNG3 11p11 guanine nucleotide binding protein (G protein), gamma 3 DKFZp762N1910 11q12.3 hypothetical protein DKFZp762N1910 MGC29649 11q12.3 hypothetical protein MGC29649 ZBTB3 11q12.3 zinc finger and BTB domain containing 3 POLR2G 11q13.1 polymerase (RNA) II (DNA directed) polypeptide G TAF6L 11q13.1 TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa LOC387617 11 hypothetical gene supported by NM_018336 LOC374395 11q12.3 similar to RIKEN cDNA 1810059G22 NXF1 11q12-q13 nuclear RNA export factor 1 STX5A 11cen-q12.1 syntaxin 5A FLJ10439 11q12.3 hypothetical protein FLJ10439 SLC3A2 11q12-q22 solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 CHRM1 11q12-q13 cholinergic receptor, muscarinic 1 SLC22A6 11q13.1-q13.2 solute carrier family 22 (organic anion transporter), member 6 SLC22A8 11q11.7 solute carrier family 22 (organic anion transporter), member 8
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    3 - 914 8.3 75 - 2004 15314181
    EXPRESSION
    Type widely
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Nervousbrain   highly Homo sapiens
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Nervouscentral    Homo sapiens
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    mono polymer heteromer , trimer
    HOMOLOGY
    interspecies homolog to C.elegans f08b6.2
    Homologene
    FAMILY
  • G protein gamma family
  • CATEGORY regulatory , receptor membrane G
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • regulatory subunit
  • activation of MAPK
  • playing roles in differentiation and development
  • involvement in the developing mammalian enteric nervous system
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling signal transduction
    a component
  • heterotrimeric G protein complexes
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
  • G protein alpha subunit and beta subunit, KSR1
  • cell & other
    REGULATION
    induced by strongly induced in activated CD4+ T-cells
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS