Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol GNG3 contributors: mct - updated : 09-03-2009
HGNC name guanine nucleotide binding protein (G protein), gamma 3
HGNC id 4405
Location 11q12.3      Physical location : 62.475.113 - 62.476.677
Synonym name
  • guanine nucleotide-binding protein gamma-3 subunit
  • NBP gamma-3
  • guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
  • Synonym symbol(s) GNGT3, IG, SG
    DNA
    TYPE functioning gene
    SPECIAL FEATURE head to head
    text head to head with BSCL2
    STRUCTURE 1.57 kb     3 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Map cen - D11S1765 - ADRBK1 - D11S2237E - D11S3598 - GNG3 - D11S4063 - D11S2422 - CD5 - D11S913 - qter
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    3 - 914 8.3 75 - 2004 15314181
    EXPRESSION
    Type widely
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Nervousbrain   highly Homo sapiens
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Nervouscentral    Homo sapiens
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    mono polymer heteromer , trimer
    HOMOLOGY
    interspecies homolog to C.elegans f08b6.2
    Homologene
    FAMILY
  • G protein gamma family
  • CATEGORY regulatory , receptor membrane G
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • regulatory subunit
  • activation of MAPK
  • playing roles in differentiation and development
  • involvement in the developing mammalian enteric nervous system
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling signal transduction
    a component
  • heterotrimeric G protein complexes
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
  • G protein alpha subunit and beta subunit, KSR1
  • cell & other
    REGULATION
    induced by strongly induced in activated CD4+ T-cells
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS