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FLASH GENE
Symbol GNG13 contributors: KTN/npt - updated : 05/11/2008
HGNC name guanine nucleotide binding protein (G protein), gamma 13
HGNC id 14131
Location 16p13.3      Physical location : 848.043 - 850.733
Synonym name G gamma subunit, clone H2-35
Synonym symbol(s) H2-35, G(gamma)13
DNA
TYPE functioning gene
STRUCTURE 2.69 kb     3 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status confirmed
Physical map
SOLH 16p13.3 small optic lobes homolog (Drosophila) LOC146325 16p13.3 similar to hypothetical protein FLJ13841 FLJ36208 16p13.3 hypothetical protein FLJ36208 PIGQ 16p13.3 phosphatidylinositol glycan, class Q RAB40C 16p13.3 RAB40C, member RAS oncogene family WFIKKN 16p13.3 RAB40C, member RAS oncogene family MGC13114 16p13.3 hypothetical protein MGC13114 LOC388198 16 LOC388198 MGC15416 16p13.3 hypothetical protein MGC15416 KIAA1924 16p13.3 hypothetical protein KIAA1924 LOC197336 16p13.3 similar to RIKEN cDNA 3230401M21 [Mus musculus] ARHT2 16p13.3 ras homolog gene family, member T2 RHBDL1 16p13.3 rhomboid, veinlet-like 1 (Drosophila) STUB1 16p13.3 STIP1 homology and U-Box containing protein 1 LOC339123 16p13.3 similar to RIKEN cDNA 2610003J06 DKFZp434F054 16p13.3 hypothetical protein DKFZp434F054 MGC33974 16p13.3 hypothetical protein MGC33974 MGC2601 16p13.3 hypothetical protein MGC2601 MGC2494 16p13.3 hypothetical protein MGC2494 FLJ34512 16p13.3 hypothetical protein FLJ34512 HAGHL 16p13.3 hydroxyacyl glutathione hydrolase-like NARFL 16p13.3 nuclear prelamin A recognition factor-like MSLN 16p13.3 mesothelin RLUCL CHTF18 16p13.3 CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae) GNG13 16p13.3 guanine nucleotide binding protein (G protein), gamma 13 LOC388199 16 LOC388199 FLJ12681 16p13.3 hypothetical protein FLJ12681
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
3 - 1001 7.8 67 - -
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Visualeye   specific
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • GGL domain
  • G proton gamma subunit like motifs
  • conjugated LipoP
    mono polymer heteromer , trimer
    HOMOLOGY
    interspecies homolog to chimpanzee GNG13 (100 pc)
    Homologene
    FAMILY
  • G protein gamma family
  • CATEGORY receptor membrane G
    SUBCELLULAR LOCALIZATION     plasma membrane
    text
  • lipid-anchor
  • cytoplasmic side
  • basic FUNCTION
  • involved as a modulator or transducer in various transmembrane signaling systems
  • required for the GTPase activity with beta chain, for replacement of GDP by GTP, and for G protein-effector interaction
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling signal transduction , sensory transduction/taste
    a component
  • composed of 3 units, alpha, beta and gamma
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interacting specifically with the third PDZ domain of DLG4
  • interacting specifically with the sole PDZ domain of LIN7B
  • interacting specifically with the third PDZ domain of DLG1
  • cell & other
    REGULATION
    Other prenylation
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS