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FLASH GENE
Symbol GNG10 contributors: KTN/npt - updated : 09/09/2008
HGNC name guanine nucleotide binding protein (G protein), gamma 10
HGNC id 4402
Location 9q31.3      Physical location : 114.423.860 - 114.432.524
Synonym name Osubunit gamma-10 precursor
Synonym symbol(s) IG, SG, GNGT10
DNA
TYPE functioning gene
STRUCTURE 8.70 kb     3 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status confirmed
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
3 - 1245 7.1 68 - -
EXPRESSION
Type ubiquitous
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
conjugated LipoP
mono polymer heteromer , trimer
HOMOLOGY
interspecies homolog to rattus Gng10 (95.6 pc)
homolog to murine Gng10 (95.6 pc)
Homologene
FAMILY G protein gamma family
CATEGORY signaling , receptor membrane G
SUBCELLULAR LOCALIZATION     plasma membrane
text
  • lipid-anchor
  • cytoplasmic side
  • basic FUNCTION
  • involved as a modulator or transducer in various transmembrane signaling systems
  • required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling hormonal , signal transduction
  • hormone-mediated siganling
  • a component
  • prenylation
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interacting with beta-1 and beta-2
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS