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FLASH GENE
Symbol GNAT3 contributors: mct - updated : 25-04-2017
Location 7q21.11      Physical location : 80.087.988 - 80.141.242
Genatlas name guanine nucleotide binding protein (G protein),alpha transducing activity polypeptide 3
Synonym name gustducin alpha-3
Synonym symbol(s) GDCA
DNA
TYPE functioning gene
STRUCTURE 53.00 kb     8 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 1125 - 374 - Fehr (2007)
- - 1065 - 354 - Fehr (2007)
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinelarge intestinecolon  
cells
SystemCellPubmedSpeciesStageRna symbol
Digestiveepithelial cell
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
CATEGORY receptor membrane G
SUBCELLULAR LOCALIZATION
basic FUNCTION
  • having a role in glucose-mediated incretin release and may serve as the previously unknown gut lumen glucose sensor
  • required for the enhanced expression of SLC5A1 shown by enterocytes in response to luminal sugars or sweeteners
  • TAS1R3 and its associated heterotrimeric GNAT3 are involved
  • in sweet and umami sensing in taste cells
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling signal transduction
    G protein coupled receptor protein signaling pathway
    a component
    INTERACTION
    DNA
    RNA
    small molecule nucleotide,
    GTP binding
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS