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FLASH GENE
Symbol GMCL1 contributors: - updated : 14-06-2006
HGNC name germ cell-less homolog 1 (Drosophila)
HGNC id 23843
Location 2p13.3      Physical location : 70.056.817 - 70.106.730
Synonym name germ cell-less protein-like 1
Synonym symbol(s) BTBD13, FLJ13057, GCL, GCL1
DNA
TYPE functioning gene
STRUCTURE 49.00 kb     14 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinesmall intestine   
 mouthtongue   
Endocrineneuroendocrinepituitary   
Lymphoid/Immunethymus    
 tonsils    
Reproductivefemale systemovary   
 male systemtestis   
Respiratoryrespiratory tracttrachea   
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connectiveadipose   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
one BTB (POZ) domain
HOMOLOGY
interspecies homolog to murine Gmcl1 (91.4pc)
homolog to rattus Gmcl1 (90.8pc)
Homologene
FAMILY
CATEGORY regulatory
SUBCELLULAR LOCALIZATION     intracellular
intracellular,nuclear envelope
text nuclear matrix component
basic FUNCTION
  • transcriptional repressor activity
  • involved in spermatogenesis, either directly or by influencing genes that play a more direct role in the process
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS reproduction/sex
    text spermatogenesis
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein interacting with TMPO-beta, TSG101, TFDP2, and EMD
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS