Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | GLIPR1 | contributors: mct - updated : 27-08-2013 |
HGNC name | GLI pathogenesis-related 1 (glioma) |
HGNC id | 17001 |
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Location | 12q21.2 Physical location : 75.874.512 - 75.895.715 |
Synonym name | |
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Synonym symbol(s) | GLIPR, RTVP1, CRISP7 |
DNA |
TYPE | functioning gene |
STRUCTURE | 21.20 kb 6 Exon(s) |
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10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | N | status | provisional |
RNA |
TRANSCRIPTS | type | messenger |
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text | 3 predominant mRNAs of 4.2, 3.2, and 1.1 kb (Rich) |
EXPRESSION |
Type | widely |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
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tissue |
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cell lineage
cell lines
| glioblastoma multiform/astrocytoma | fluid/secretion
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at STAGE |
physiological period | fetal |
Text | kidney only |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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HOMOLOGY |
intraspecies | homolog to testis-specific protein, TPX1 |
Homologene |
FAMILY | CRISP family, CAP superfamily |
CATEGORY | tumor suppressor |
SUBCELLULAR LOCALIZATION | extracellular |
| plasma membrane |
| intracellular |
intracellular,cytoplasm,organelle,membrane | |
intracellular,cytoplasm,organelle,endoplasmic reticulum |
basic FUNCTION | |
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CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein | TP53 target gene |
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) |
Other morbid association(s) |
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Susceptibility |
Variant & Polymorphism
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Candidate gene
Marker
| Therapy target
| RTVP1b represents a potential prognostic marker and therapeutic target in gliomas |
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ANIMAL & CELL MODELS |