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FLASH GENE
Symbol GH2 contributors: - updated : 03-01-2006
HGNC name growth hormone 2
HGNC id 4262
Location 17q23      Physical location : 61.957.571 - 61.959.223
Synonym name
  • placenta-specific growth hormone
  • growth hormone 2 (V,variant)
    • Synonym symbol(s) GHV, GHL, GH-V, hGH-V
    DNA
    TYPE functioning gene
    SPECIAL FEATURE component of a cluster
    STRUCTURE 1.00 kb     4 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status confirmed
    Map cen - GH1 - CSHL1 - CSH1 - GH2 - CSH2 - qter
    Authors Phillips (83)
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - - 22000 - - - Boguszewski
    retaining intron IV, with a transmembrane domain
    - splicing 20000 - - placenta Boguszewski
    - splicing 24000 - 219 placenta Boguszewski
    without a transmembrane domain
    EXPRESSION
    Type restricted
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Reproductivefemale systemplacenta  specific
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period pregnancy
    Text placenta
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    mono polymer monomer , dimer , trimer , tetramer , pentamer
    HOMOLOGY
    Homologene
    FAMILY somatotropin/prolactin family
    CATEGORY signaling hormone
    SUBCELLULAR LOCALIZATION extracellular
        intracellular
    intracellular,cytoplasm
    intracellular,nucleus
    basic FUNCTION
  • playing an important role in growth control
  • stimulating both the differentiation and proliferation of myoblasts, amino acid uptake and protein synthesis in muscle and other tissues
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS development
    text growth
    PATHWAY
    metabolism
    signaling hormonal
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS