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FLASH GENE
Symbol GGNBP2 contributors: np/ - updated : 28-02-2005
HGNC name gametogenetin binding protein 2
HGNC id 19357
Location 17q12      Physical location : 34.900.736 - 34.946.274
Synonym name
  • C3HC4-type zinc finger protein
  • laryngeal carcinoma related gene 1
  • dioxin inducible factor-3
  • zinc finger protein 403
  • Synonym symbol(s) DIF3, LZK1, DIF-3, LCRG1, ZFP403, FLJ21230, FLJ22561, ZNF403, FLJ42090
    DNA
    TYPE functioning gene
    STRUCTURE 45.54 kb     14 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    14 - 2869 79 697 - -
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart    
    Endocrinepancreas    
    Reproductivemale systemtestis  highly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Muscularstriatumskeletal  
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a zinc-finger motif at its N-terminus
  • one potential site for phosphorylation by casein kinase II
  • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY tumor suppressor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    intracellular,nucleus
    basic FUNCTION
  • implicated in spermatogenesis
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --low  
    in laryngeal carcinoma
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS