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Symbol GDPD4 contributors: mct/npt - updated : 18-01-2010
HGNC name glycerophosphodiester phosphodiesterase domain containing 4
HGNC id 24849
Location 11q13.5      Physical location : 76.927.603 - 76.998.463
Synonym name
  • GDPD domain containing protein
  • glycerophosphodiester phosphodiesterase 6
    • Synonym symbol(s) GDE6, UGPQ
    EC.number 3.1.-.-
    DNA
    TYPE functioning gene
    STRUCTURE 70.86 kb     16 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    16 - 2545 - 520 - Nogusa (2004)
    EXPRESSION
    Type restricted
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Endocrineadrenal gland    
    Lymphoid/Immunespleen    
    Reproductivefemale systembreastmammary gland  
     male systemtestis   
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • GP-PDE-like extracellular motif expressed during osteoblast differentiation and playing an important role in the regulation of cytoskeletal modification
  • seven putative transmembrane regions
    • HOMOLOGY
    Homologene
    FAMILY
  • glycerophosphoryl diester phosphodiesterase (GDPD) family
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • serpentine membrane protein, having glycerophosphodiester phosphodiesterase activity
  • hydrolyzing deacylated phospholipids to G3P and the corresponding alcohols
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism carbohydrate
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS