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FLASH GENE
Symbol GDF7 contributors: - updated : 08-01-2005
HGNC name growth differentiation factor 7
HGNC id 4222
Location 2p24-p23      Physical location : 20.866.423 - 20.871.250
DNA
TYPE functioning gene
SPECIAL FEATURE escaping inactivation
STRUCTURE 4.00 kb     2 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
RDH14 2p24.1 retinol dehydrogenase 14 (all-trans and 9-cis) NT5C1B 2p24.1 5'-nucleotidase, cytosolic IB LOC388927 2 LOC388927 OSR1 3p22-p21.3 oxidative-stress responsive 1 LOC130500 2p24.3 similar to Uncharacterized hematopoietic stem/progenitor cells protein MDS029 LOC130502 2p24.3 similar to CG14894-PA KIAA1336 2p24.3 KIAA1336 protein MATN3 2p24-p23 matrilin 3 LAPTM4A 2p24.3 lysosomal-associated protein transmembrane 4 alpha LOC391355 2 similar to 40S ribosomal protein S16 SDC1 2p24.1 syndecan 1 LOC151457 2p24.3 similar to GTP-binding protein PUM2 2p22-p21 pumilio homolog 2 (Drosophila) ARHB 2pter-p12 ras homolog gene family, member B LOC151451 2p24.2 hypothetical LOC151451 LOC388928 2 similar to hypothetical protein LOC91942 FLJ14249 2p24.2 HS1-binding protein 3 GDF7 2p23-p24 growth differentiation factor 7 FLJ21820 2p24.2 hypothetical protein FLJ21820 APOB 2p24-p23 apolipoprotein B (including Ag(x) antigen) LOC388929 2 similar to tudor domain containing 6 protein LOC388930 2 LOC388930
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrainhindbrainmedulla oblongata  
Urinarykidney    
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period embryo
Text in the imaginal discs associated with establishment of the proximal-distal axis of the appendages, and midgut mesoderm
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
mono polymer homomer , dimer
HOMOLOGY
Homologene
FAMILY TGFbeta family
CATEGORY transcription factor
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm
basic FUNCTION
  • required for the proper development of the embryonic dorsal hypoderm
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS development
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS