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FLASH GENE
Symbol GDF7 contributors: - updated : 08-01-2005
HGNC name growth differentiation factor 7
HGNC id 4222
Location 2p24-p23      Physical location : 20.866.423 - 20.871.250
DNA
TYPE functioning gene
SPECIAL FEATURE escaping inactivation
STRUCTURE 4.00 kb     2 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrainhindbrainmedulla oblongata  
Urinarykidney    
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period embryo
Text in the imaginal discs associated with establishment of the proximal-distal axis of the appendages, and midgut mesoderm
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
mono polymer homomer , dimer
HOMOLOGY
Homologene
FAMILY TGFbeta family
CATEGORY transcription factor
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm
basic FUNCTION
  • required for the proper development of the embryonic dorsal hypoderm
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS development
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS