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FLASH GENE
Symbol GCNT4 contributors: - updated : 09-03-2006
HGNC name glucosaminyl (N-acetyl) transferase 4, core 2 (beta-1,6-N-acetylglucosaminyltransferase)
HGNC id 17973
Location 5q12      Physical location : 74.323.289 - 74.326.724
Synonym name
  • beta-1,6-N-acetylglucosaminyltransferase 4, core 25 branching enzyme in O glycans
  • core 2 beta-1,6-N-acetylglucosaminyltransferase 3
  • Synonym symbol(s) GCNT4, B6GLcNacT, C2GNT3
    DNA
    TYPE functioning gene
    STRUCTURE 3.00 kb     1 Exon(s)
    text structure all coding region in a single exon
    MAPPING cloned Y linked   status provisional
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type widely
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    blood / hematopoieticthymus   highly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Lymphoid    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a N terminal cytoplasmic domain
  • a transmembrane segment
  • an extracytoplasmic N terminal stem region
  • catalytic domain
  • secondary structure four N-glycosylation
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     plasma membrane
    text type II integral membrane protein
    basic FUNCTION
  • acceptor beta1, 6-N-acetylglucosaminyltransferases (beta6GlcNAc-Ts) is an important step in mucin-type biosynthesis
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    text mucin biosynthesis
    PATHWAY
    metabolism carbohydrate
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS