Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | GCM2 | contributors: mct/shn - updated : 30-11-2016 |
HGNC name | glial cells missing homolog 2 (Drosophila) |
HGNC id | 4198 |
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Corresponding disease |
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Location | 6p24.2 Physical location : 10.873.458 - 10.882.098 | ||||
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Synonym symbol(s) | GCMB, RP3-417M14.3, hGCMb |
DNA |
TYPE | functioning gene |
STRUCTURE | 8.64 kb 5 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | N | status | confirmed |
Map | pter - D6S410 - D6S470 - GCM2 - D6S1034 - D6S1721 - cen |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | restricted |
cell lineage
cell lines
| D283 Med, D341 Med ( | fluid/secretion
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at STAGE |
physiological period | fetal |
Text | brain |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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HOMOLOGY |
interspecies | homolog to Drosophila glial cells missing gene |
ortholog to Gcm2, Mus musculus | |
ortholog to gcm2, Danio rerio | |
ortholog to Gcm2, Rattus norvegicus | |
ortholog to GCM2, pan troglodytes |
Homologene |
FAMILY |
CATEGORY | DNA associated , transcription factor |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,nucleus,chromatin/chromosome |
basic FUNCTION | |
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hormone (PTH)- secreting cells of the parathyroid gland | |
and is essential for their development (Canaff 2009) | |
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CELLULAR PROCESS | nucleotide, transcription |
PHYSIOLOGICAL PROCESS | development |
text | organogenesis |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA | binding |
RNA |
small molecule |
protein | |
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cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | FIHP , HRPT4 |
Susceptibility | to primary hyperparathyroidism (PHPT) |
Variant & Polymorphism SNP | |
Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |
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