Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | GBA3 | contributors: SGE - updated : 21-02-2008 |
HGNC name | glucosidase, beta, acid 3 (cytosolic) |
HGNC id | 19069 |
|
Location | 4p15.31 Physical location : 22.694.547 - 22.821.191 |
Synonym name | |
| |
Synonym symbol(s) | CBGL1, GLUC, KlrP, MGC104276, MGC126878 |
EC.number | 3.2.1.21 |
DNA |
TYPE | functioning gene |
STRUCTURE | 126.00 kb 5 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
---|
MAPPING | cloned | Y | linked | N | status | provisional |
RNA |
TRANSCRIPTS | type | messenger |
---|
|
EXPRESSION |
Type |
constitutive of |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
|
tissue |
|
cell lineage
cell lines
| down regulated in renal cell carcinomas and hepatocellular carcinomas | fluid/secretion
| |
at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
| one beta-glucosidase-like domain with two conserved active-site glu residues |
HOMOLOGY |
interspecies | homolog to dog GBA3 (87.8pc) |
Homologene |
FAMILY | glycosyl hydrolase 1 family, Klotho subfamily |
CATEGORY | enzyme |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm,cytosolic |
basic FUNCTION | |
| |
|