Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol GALNT7 contributors: mct - updated : 10-06-2011
HGNC name UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
HGNC id 4129
Location 4q31.1      Physical location : 174.089.903 - 174.245.117
Synonym name
  • pp-GaNTase 7
  • polypeptide GalNAc transferase 7
  • Synonym symbol(s) GalNAcT7, GALNAC-T7
    EC.number 2.4.1.41
    DNA
    TYPE functioning gene
    STRUCTURE 155.21 kb     12 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    12 - 4339 75.2 657 - 2010 20977886
    EXPRESSION
    Type widely
    constitutive of
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • near the N terminus, a stem region, a lumenal catalytic domain
  • a GT1 motif and Ga1/Ga1 NAc transferase motif
  • a C terminal ricin/lectin-like domain
  • a QXW lectin repeat
  • HOMOLOGY
    interspecies ortholog to Drosophila dGalNAc-T2
    Homologene
    FAMILY
  • glycosyltransferase 2 family
  • GalNAc-T subfamily
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,Golgi
    basic FUNCTION
  • controls mucin-type O-linked protein glycosylation and transfer of N-acetylgalactosamine to serine and threonine amino acid residues, exclusively in partially GalNAc glycosylated peptides
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism carbohydrate
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule cofactor,
  • Ca2+
  • Mn2+
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS