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FLASH GENE
Symbol GALNT10 contributors: mct - updated : 10-06-2011
HGNC name UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)
HGNC id 19873
Location 5q33.2      Physical location : 153.570.294 - 153.800.541
Synonym name
  • galactosamine:UDP-N-acetyl-alpha-D-polypeptide T10
  • GalNAc transferase 10
  • N-acetylgalactosaminyltransferase 10 (GalNAc-T10)
  • Synonym symbol(s) NGALT10, DKFZp586H0623, FLJ00205, FLJ11715, GalNAcT10, pp-GalNAc-T10
    EC.number 2.4.1.41
    DNA
    TYPE functioning gene
    STRUCTURE 229.52 kb     12 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status confirmed
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    12 - 3852 69 603 - 2010 20977886
    - - 4361 31.5 274 - 2010 20977886
    EXPRESSION
    Type widely
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveintestinesmall intestine   
     stomach    
    Endocrinepancreas    
     thyroid    
    Lymphoid/Immunespleen    
    Reproductivefemale systemovary   
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • near the N terminus,a stem region
  • a lumenal catalytic domain
  • a GT1 motif and Ga1/Ga1 NAc transferase motif
  • a C terminal ricin/lectin-like domain
  • a QXW lectin repeat
  • HOMOLOGY
    intraspecies paralog to GALNT7
    Homologene
    FAMILY
  • glycosyltransferase 2 family
  • GalNAc-T subfamily
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,Golgi
    basic FUNCTION
  • catalyzing the initial reaction in O-linked (mucin type) oligosaccharide biosynthesis
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism carbohydrate
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule cofactor,
  • Ca2+
  • Mn2+
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS