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FLASH GENE
Symbol FUT10 contributors: SGE/npt - updated : 26-06-2009
HGNC name fucosyltransferase 10 (alpha (1,3) fucosyltransferase)
HGNC id 19234
Location 8p12      Physical location : 33.228.345 - 33.330.664
Synonym name
  • alpha 1,3-fucosyl transferase
  • galactoside 3-L-fucosyltransferase 10
  • Synonym symbol(s) MGC11141, Fuc-TX
    EC.number 2.4.1.-
    DNA
    TYPE functioning gene
    STRUCTURE 102.32 kb     5 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Physical map
    DCTN6 8p12-p11 dynactin 6 LOC392209 8 similar to heat shock protein (hsp-2) LOC92755 8p21.1 hypothetical gene LOC92755 RBPMS 8p12-p11 RNA binding protein with multiple splicing GTF2E2 8p12-p11 general transcription factor IIE, polypeptide 2, beta 34kDa GSR 8p21.1 glutathione reductase D8S2298E 8p12-p11.2 Homo sapiens reproduction 8 (D8S2298E), mRNA. PPP2CB 8p12-p11.2 protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform TEX15 8p12 testis expressed sequence 15 PURG 8p11 purine-rich element binding protein G WRN 8p12-p11.2 Werner syndrome LOC157589 8p12 similar to potassium channel tetramerisation domain containing 9 NRG1 8p21-p12 neuregulin 1 FUT10 8p12 fucosyltransferase 10 (alpha (1,3) fucosyltransferase) LOC84549 8p12 RNA binding protein FLJ23263 8p12 hypothetical protein FLJ23263 RNF122 8p12 ring finger protein 122 MGC1136 8p12 hypothetical protein MGC1136 LOC392210 8 similar to VENT-like homeobox 2; hemopoietic progenitor homeobox protein VENTX2 LOC392211 8 similar to Ribosomal protein L6 HCP21 8p12 cytochrome c, somatic pseudogene LOC137107 8p12 similar to ribosomal protein L10a LOC389646 8 hypothetical gene supported by X89401; NM_000982 UNC5D 8p11.23-p11.22 unc-5 homolog D (C. elegans)
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - splicing - - 391 - Mollicone 2009
  • expressed in embryos
  • soluble protein
  • - splicing - - 419 - Mollicone 2009
  • expressed in embryos
  • type II trans-membrane topology, retained to ER by a membrane retention signal at the NH2 termini
  • 5 splicing 3549 55.9 479 - Mollicone 2009
  • expressed in adult brain
  • type II trans-membrane topology, retained to ER by a membrane retention signal at the NH2 termini
  • a COOH-ER membrane retention signal
  • EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    interspecies homolog to murine Fut10 (82.0pc)
    Homologene
    FAMILY
  • glycosyltransferase 10 family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,endoplasmic reticulum
    basic FUNCTION
  • transferring glycosyl groups
  • CELLULAR PROCESS protein, post translation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism carbohydrate
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS