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FLASH GENE

Symbol

FOXO3

contributors: mct - updated : 30-09-2016

HGNC name	forkhead box O3
HGNC id	3821

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	6q21      Physical location : 108.881.025 - 109.005.971
Synonym name	forkhead, drosophila, homolog of, in rhabdomyosarcoma-like 1
	myeloid/lymphoid of mixed-lineage leukemia (trithorax (Drosophila)homolog 8)
	forkhead box O3A
	AF6q21 protein
Synonym symbol(s)	FKH1L1, FKHRL1, AF6q21, MLLT8, FKHR2, FKHRL1P2, FOXO3A, MGC12739, MGC31925, FOXO2, DKFZp781A0677

DNA

TYPE	breakpoint
STRUCTURE	124.95 kb     4 Exon(s)

MAPPING

cloned

Y

linked

N

status

confirmed

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed NM_001455 3 splicing 7341 NP_001446 71 673 - 2008 18344987 both variants differ in the 5' end but encode the same protein NM_201559 4 splicing 7314 NP_963853 71 673 - 2008 18344987

EXPRESSION

Type	ubiquitous

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Hearing/Equilibrium ear       highly Visual eye       highly

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Blood / Hematopoietic bone marrow       Connective adipose     highly Muscular striatum skeletal   highly

cells

System Cell Pubmed Species Stage Rna symbol Blood/Hematopoietic megakaryocyte

cell lineage
cell lines	rhabdomyosarcoma line
fluid/secretion

at STAGE

physiological period

embryo

Text	erythroid line

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

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