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FLASH GENE
Symbol FOXB2 contributors: npt/KTN - updated : 11/12/2008
HGNC name forkhead box B2
HGNC id 23315
Location 9q21.13      Physical location : 79.634.570 - 79.635.869
Synonym symbol(s) bA159H20.4
DNA
TYPE functioning gene
STRUCTURE 1.30 kb     1 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
1 - 1299 45.5 432 - Humphray (2004)
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a fork-head DNA-binding domain
    • HOMOLOGY
    interspecies homolog to dog FOXB2 (90.7 pc)
    homolog to chimpanzee FOXB2 (99.1 pc)
    homolog to cow FOXB2 (93.3 pc)
    homolog to rattus Foxb2 (92.2 pc)
    homolog to murine Foxb2 (92 pc)
    Homologene
    FAMILY
  • forkhead family of transcriptional activator
    • CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • involved in regulation of transcription
    • CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding to sequence-specific DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS