Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol FOXB1 contributors: mlc/np - updated : 09-11-2007
HGNC name forkhead box B1
HGNC id 3799
Location 15q21-q26      Physical location : 60.296.420 - 60.298.142
Synonym name transcription factor-like 5
Synonym symbol(s) HFKH5, FKH5
DNA
TYPE functioning gene
SPECIAL FEATURE head to head
STRUCTURE 1.00 kb     1 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
LOC388124 15 LOC388124 FLJ14957 15q21.2 hypothetical protein FLJ14957 FLJ30973 15q21.2 hypothetical protein FLJ30973 GRINL1A 15q22.1 glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A ALDH1A2 15q21.2 aldehyde dehydrogenase 1 family, member A2 AQP9 15q22.1-q22.2 aquaporin 9 LOC145780 15q21.2 hypothetical LOC145780 LIPC 15q21-q22.2 lipase, hepatic ADAM10 15q22 a disintegrin and metalloproteinase domain 10 KIAA1164 15q21.3 hypothetical protein KIAA1164 LOC390587 15 similar to zinc finger protein 444; endothelial zinc finger protein 2 FLJ13213 15q21.3 hypothetical protein FLJ13213 RNF111 15q21 ring finger protein 111 CCNB2 15q21.3 cyclin B2 MYO1E 15q21-q22 myosin IE LDHL 15q21.3 lactate dehydrogenase A -like LOC390588 15 similar to TGF beta-inducible nuclear protein 1 (Hairy cell leukemia protein 1) (HUSSY-29) MGC26690 15q21.3 hypothetical protein MGC26690 GCNT3 15q21.3 glucosaminyl (N-acetyl) transferase 3, mucin type GTF2A2 15q21.2 general transcription factor IIA, 2, 12kDa BNIP2 15q11.2 BCL2/adenovirus E1B 19kDa interacting protein 2 LOC145767 LOC390589 15 similar to ATP-dependent RNA helicase DDX18 (DEAD-box protein 18) (Myc-regulated DEAD-box protein) (MrDb) FOXB1 15q21-q26 forkhead box B1 ANXA2 15q21-q22 annexin A2 NARG2 15q21.3 NMDA receptor-regulated gene 2 RORA 15q21-q22 RAR-related orphan receptor A HCP38 15q21.3 cytochrome c, somatic pseudogene LOC390590 15 similar to RAR-related orphan receptor A isoform a; RAR-related orphan receptor alpha; retinoic acid receptor-related orphan receptor alpha; transcription factor RZR-alpha; ROR-alpha FLJ20136 LOC145741 15q21.3 hypothetical LOC145741 LOC390591 15 similar to nucleophosmin LOC388125 15 similar to hypothetical LOC237397 FLJ38723 15q21.3 hypothetical protein FLJ38723 TLN2 15q15-q21 talin 2 LOC390592 15 similar to TSH receptor suppressor element-binding protein-1; TSEP-1
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
1 - 1459 34 324 - Kimura (2006)
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrain    
Reproductivefemale systemuterus   
Urinarykidney    
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period embryo
Text expression in the developing neural tube is soon restricted to the ventral and caudal diencephalon
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a forkhead (FH, winged helix) domain
  • two loops-wings on the C-terminal side of helix-turn-helix homeo domain
  • HOMOLOGY
    interspecies homolog to Drosophila homeo forkhead DNA binding domain
    Homologene
    FAMILY
  • HNF-3 FKH forkhead family of transcriptional activator
  • CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome
    basic FUNCTION
  • embryonic transcriptional activator
  • CELLULAR PROCESS nucleotide, transcription
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS