SUBCELLULAR LOCALIZATION
| extracellular
|
| intracellular
|
| intracellular,cytoplasm,organelle,membrane
|
| intracellular,cytoplasm,organelle,endoplasmic reticulum
|
| intracellular,cytoplasm,organelle,Golgi
|
| intracellular,nucleus
|
text
| transiently expressed at the early stage of adipocyte differentiation |
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localizes to the Golgi network, and its correct localization is essential for its transforming function |
basic FUNCTION
| functioning as a positive regulator of adipogenesis |
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plays important roles in adipocyte differentiation |
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essential for the survival of newborns just after birth and important for cell proliferation, adhesion, spreading and migration |
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reciprocally regulates differentiation of adipocytes and osteoblast, and functions as a positive regulator in adipocyte differentiation and as a negative regulator in osteoblast differentiation |
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regulator of adipogenesis and osteogenesis |
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having an indispensable role in lung maturation, especially the maturation and differentiation of ATII cells |
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is an important oncogenic driver gene of the 3q amplicon, adding to the growing list of oncogenic drivers within this commonly amplified region |