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FLASH GENE
Symbol FKHL18 contributors: - updated : 20-08-2007
HGNC name forkhead-like 18 (Drosophila)
HGNC id 3735
Location 20q11.1-q11.2      Physical location : -
Genatlas name transcription factor-like 18
Synonym name
  • forkhead-related activator 10
  • forkhead-related transcription factor 10
    • Synonym symbol(s) FREAC10
    DNA
    TYPE functioning gene
    STRUCTURE 1.00 kb     1 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked   status provisional
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type restricted
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularvesselsaorta  predominantly
    Reproductivefemale systemplacenta  highly
     male systemprostate  highly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Muscularstriatumskeletal highly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a forkhead (FH,winged helix) domain with two loops-wings on the C-terminal side of helix-turn-helix domain
    • HOMOLOGY
    interspecies homolog to Drosophila homeo fork head DNA binding domain
    homolog to murine forkhead gene Fhk3
    Homologene
    FAMILY HNF-3 forkhead family of transcriptional activators
    CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome
    basic FUNCTION unknown
    CELLULAR PROCESS nucleotide, transcription
    PHYSIOLOGICAL PROCESS development
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS