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FLASH GENE
Symbol FIGN contributors: - updated : 23-01-2006
HGNC name fidgetin
HGNC id 13285
Location 2q24.3      Physical location : 164.464.117 - 164.592.513
DNA
TYPE functioning gene
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularvessel   highly
Digestiveliver   highly
 pancreas exocrine   highly
Reproductivemale systemprostate  moderately
Skin/Tegumentskin   moderately
Urinarybladder   predominantly
 kidney   moderately
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connectivebone   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • shikimate kinase domain
  • HOMOLOGY
    interspecies ortholog to rattus Fign predicted
    ortholog to murine Fign
    intraspecies homolog to SPG4
    Homologene
    FAMILY
  • AAA protein family
  • meiotic or subfamily 7 group of ATPases associated with diverses cellular activities
  • CATEGORY chaperone/stress
    SUBCELLULAR LOCALIZATION
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS development
    text
  • embryonic development
  • PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule nucleotide,
    ATP
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS
  • "fidget" mutant mice