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FLASH GENE
Symbol FGR contributors: - updated : 20-07-2006
HGNC name Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
HGNC id 3697
Location 1p36.2-p36.1      Physical location : 27.938.802 - 27.961.727
Synonym name
  • c-SRC-2 protein
  • p55-c-FGR protein
    • Synonym symbol(s) SRC2, FLJ43153, c-fgr, p55c-fgr
    EC.number 2.7.1.112
    DNA
    TYPE functioning gene
    STRUCTURE 11.00 kb     11 Exon(s)
    Genomic sequence alignment details
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked Y status confirmed
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type widely
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Lymphoid/Immunespleen   highly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Connectiveadipose  highly
    cell lineage
    cell lines
    fluid/secretion lymph highly
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a protein kinase domain
  • a SH2 domain
  • a SH3 domain
    • HOMOLOGY
    interspecies homolog to feline Gardner-Rasheed sarcoma viral (c-fgr) oncogene
    Homologene
    FAMILY SRC family (signal transduction)
    CATEGORY enzyme , protooncogene
    SUBCELLULAR LOCALIZATION
    basic FUNCTION target for beta 2 integrin-induced c-CBL-mediated ubiquitination in adherent neutrophils
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein binds PTPNS1
    cell & other i5 membrane associated
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS