Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | FGA | contributors: npt/ - updated : 24-04-2006 |
HGNC name | fibrinogen alpha chain |
HGNC id | 3661 |
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Corresponding disease |
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Location | 4q32.1 Physical location : 155.504.279 - 155.511.897 | ||||||
Synonym name | |||||||
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Synonym symbol(s) | Fib2, MGC119422, MGC119423, MGC119425 |
DNA |
TYPE | functioning gene |
SPECIAL FEATURE | component of a cluster |
text | see FG@ |
STRUCTURE | 7.62 kb 6 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | Y | status | confirmed |
Map | cen - FGG - FGA - FGB - qter |
Authors | Aschbacher (1985) |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | restricted |
constitutive of |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||
organ(s) |
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tissue |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
physiological period | fetal |
Text | liver |
IMPRINTING | paternally |
text | paternally imprinted in any cases of a fibrinogenemia |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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isoforms | Precursor | cleaved by thrombin in the N terminal region |
HOMOLOGY |
Homologene |
FAMILY |
CATEGORY | structural protein |
SUBCELLULAR LOCALIZATION | extracellular |
text | plasma |
basic FUNCTION |
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS | coagulation/hemostasis |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein |
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | FAMYR1 , CAFG , TRDF |
related resource | A Database For Human Fibrinogen Variants |
Susceptibility | to venous thromboembolism |
Variant & Polymorphism other | polymorphism associated to venous thromboembolism |
Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |