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FLASH GENE
Symbol FEZ2 contributors: - updated : 29-03-2004
HGNC name fasciculation and elongation protein zeta 2 (zygin II)
HGNC id 3660
Location 2p21      Physical location : 36.779.403 - 36.825.332
Genatlas name zygin-2
Synonym name
  • pre-T/NK cell associated protein (3Cl)
  • fasciculation and elongation protein zeta 2
  • Synonym symbol(s) HUM3CL
    DNA
    TYPE functioning gene
    STRUCTURE 45.00 kb     8 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    blood / hematopoieticspleen    
    Cardiovascularheart    
    Reproductivemale systemtestis   
    Respiratorylung    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Lymphoid    
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Skin/Tegumentmelanocyte
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period pregnancy
    Text placenta
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    interspecies homolog to C.elegans Unc76
    intraspecies homolog to FEZ1
    Homologene
    FAMILY zygin family
    CATEGORY signaling
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,nucleus
    basic FUNCTION ; involved in axonal outgrowth and fasciculation
  • playing an important role in the morphological changes of various cells by associating with PRKCZ in a tissue-non-specific manner.
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS nervous system
    text axon guidance
    PATHWAY
    metabolism
    signaling signal transduction
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • synaptotagmin
  • PRKCZ
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS