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FLASH GENE
Symbol FCRL1 contributors: np - updated : 14-06-2006
HGNC name Fc receptor-like 1
HGNC id 18509
Location 1q21-q22      Physical location : 157.764.195 - 157.789.940
Synonym name
  • immunoglobulin superfamily receptor translocation associated 5
  • CDNA FLJ39371 fis, clone PEBLM2007598, moderately similar to Mus
  • Synonym symbol(s) RP11-367J7.7, FCRH1, IRTA5, IFGP1, DKFZp667O1421
    DNA
    TYPE functioning gene
    SPECIAL FEATURE component of a cluster
    text component of a cluster of five IRTAs genes, contiguously located 1q21
    STRUCTURE 25.00 kb     11 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    11 - 2627 - 429 - -
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Lymphoid/Immunespleen   predominantly
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Blood/Hematopoieticgranulocyte
    Lymphoid/Immunenatural killer
    cell lineage B cell lineages mantle zone
    cell lines lymphoid and myeloid
    fluid/secretion blood
    at STAGE
    physiological period embryo
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    ITIM domain
    HOMOLOGY
    Homologene
    FAMILY
  • immunoglobulin family
  • CATEGORY receptor membrane ligand ion channel
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • may have a role in immunologic functions
  • has the potential to serve as an activating coreceptor on B cells
  • playing a role in regulating activation of normal B cells and possibly the development of neoplasia
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS immunity/defense
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS