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FLASH GENE
Symbol FCHSD2 contributors: - updated : 12-11-2005
HGNC name FCH and double SH3 domains 2
HGNC id 29114
Location 11q13.4      Physical location : 72.547.790 - 72.853.143
Synonym name
  • KIAA0769 gene product
  • SH3 multiple domains 3
  • Synonym symbol(s) SH3MD3, KIAA0769
    DNA
    TYPE functioning gene
    STRUCTURE 305.00 kb     22 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart    
    Digestiveliver    
    Nervousbrain    
    Reproductivemale systemprostate   
    Respiratorylung    
    Urinarykidney    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Blood / Hematopoieticbone marrow   
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • four SH3 domains
  • one CDC15/FES/CIP4 motif
  • one lactate/malate dehydrogenase domain
  • two coiled-coil stretches
  • one leucine zipper motif
  • HOMOLOGY
    interspecies homolog to Drosophila CG4684
    homolog to murine Fchsd2
    Homologene
    FAMILY FCHSD family
    CATEGORY transport carrier
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • having a oxidoreductase activity
  • playing a role in protein transport and mediating the assembly of large multiprotein complexes
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS