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FLASH GENE
Symbol FBXL19 contributors: - updated : 08-06-2006
HGNC name F-box and leucine-rich repeat protein 19
HGNC id 25300
Location 16p11.2      Physical location : 30.935.895 - 30.960.104
Synonym symbol(s) FBL19, MGC50505, CXXC11
DNA
TYPE functioning gene
STRUCTURE 22.00 kb     10 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinesmall intestine   
 intestinelarge intestinecolon  
Endocrineadrenal gland    
 pancreas    
 thyroid    
Respiratoryrespiratory tractlarynx   
Skin/Tegumentskin    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connectivebone   
cell lineage
cell lines
fluid/secretion lymph
at STAGE
physiological period embryo
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • one CXXC-type zinc finger
  • one F-box domain
  • four LRR (leucine-rich) repeats
  • one PHD-type zinc finger
  • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION may be involved in ubiquitination
    CELLULAR PROCESS protein, degradation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component component of SCF complex, formed by SKP1, cullin and F-box proteins
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
    ion Zn2+ binding
    protein interacting with SKP1A and CUL1
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS