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FLASH GENE
Symbol FBXL17 contributors: - updated : 18-11-2005
HGNC name F-box and leucine-rich repeat protein 17
HGNC id 13615
Location 5q21.3      Physical location : 107.194.739 - 107.717.799
Synonym name F-box only protein 13
Synonym symbol(s) DKFZP434C1715, FBXO13
DNA
TYPE functioning gene
STRUCTURE 523.00 kb     10 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrainhindbraincerebellum  
Reproductivemale systemtestis   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • one F-box domain
  • five leucine-rich repeats (LRR)
  • mono polymer complex
    HOMOLOGY
    interspecies homolog to murine Fbxo13
    Homologene
    FAMILY
    CATEGORY chaperone/stress
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • may recognizes and binds to phosphorylated proteins and promotes their ubiquitination and degradation
  • CELLULAR PROCESS protein, degradation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein binds SKP1 to form the SCF protein ligase complex
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS