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FLASH GENE
Symbol FBF1 contributors: mct/npt - updated : 12-02-2010
HGNC name Fas (TNFRSF6) binding factor 1
HGNC id 24674
Location 17q25.1      Physical location : 73.906.617 - 73.937.119
Synonym name
  • Fas binding factor 1
  • albatross
  • Synonym symbol(s) FLJ00103, FBF-1, KIAA1863, Alb, FLJ13996
    DNA
    TYPE functioning gene
    STRUCTURE 30.50 kb     29 Exon(s)
    MAPPING cloned N linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    29 - 3862 125.36 1133 - Schmidt (2000)
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Nervousnerve    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Muscular    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY structural protein
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • keratin-binding protein important for epithelial cell polarization (Sugimoto 2008)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • complexing with F2RL2 to regulate formation of the apical junctional complex (AJC) and maintain lateral membrane identity (Sugimoto 2008)
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS