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FLASH GENE
Symbol FAR2 contributors: mct - updated : 07-03-2009
HGNC name fatty acyl CoA reductase 2
HGNC id 25531
Location 12p11.22      Physical location : 29.376.597 - 29.487.005
Synonym name
  • male sterility domain containing 1
  • short chain dehydrogenase/reductase family 10E, member 2
  • Synonym symbol(s) SDR10E2, MLSTD1, FLJ10462
    EC.number 1.2.1.-
    DNA
    TYPE functioning gene
    STRUCTURE 110.40 kb     12 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    12 - 2235 59.31 515 - -
    EXPRESSION
    Rna function brain
    Type restricted
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Lymphoid/Immunespleen    
    Reproductivemale systemtestis   
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Blood / hematopoieticbone marrow   
    Muscularstriatumskeletal  
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY
  • fatty acid receptor family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,peroxisome
    intracellular,cytoplasm,organelle,endoplasmic reticulum
    basic FUNCTION
  • reduced fatty acids to fatty alcohols
  • involved in the metabolism of a large variety of compounds, including steroid hormones, prostaglandins, retinoids, lipids and xenobiotics
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule cofactor,
  • NADPH
  • protein
  • preferred saturated fatty acids of 16 or 18 carbons as substrats
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS