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FLASH GENE
Symbol FAP contributors: npt/ - updated : 20-12-2006
HGNC name fibroblast activation protein, alpha
HGNC id 3590
Location 2q23      Physical location : 163.027.200 - 163.100.045
Synonym name
  • seprase
  • integral membrane serine protease
  • 170 kDa melanoma membrane-bound gelatinase
    • Synonym symbol(s) FAPA, DPPIV, DKFZp686G13158
    EC.number 3.4.21.-
    DNA
    TYPE functioning gene
    STRUCTURE 72.85 kb     26 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status confirmed
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    26 - 2788 87.6 760 - -
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Connective    
    Epithelial    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    intraspecies homolog to seprase
    Homologene
    FAMILY
  • peptidase S9B family
    • CATEGORY enzyme , signaling growth factor
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • fibroblast activation protein alpha
  • type II integral serine protease
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS