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FLASH GENE
Symbol FAM20C contributors: - updated : 17-10-2007
HGNC name family with sequence similarity 20, member C
HGNC id 22140
Corresponding disease
OBDL osteosclerotic bone dysplasia, letal
Location 7p22.3      Physical location : 192.968 - 300.711
Synonym name
  • protein FAM20C
  • dentin matrix protein 4
  • Synonym symbol(s) DMP4
    DNA
    TYPE functioning gene
    STRUCTURE 15.00 kb     3 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type widely
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestivesalivary gland   predominantly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period embryo
    Text umbilical cord
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    isoforms Precursor
    HOMOLOGY
    Homologene
    FAMILY FAM20 family
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION extracellular
        intracellular
    intracellular,nucleus
    text secreted
    basic FUNCTION
  • potential functions in regulating differentiation and function of hematopoietic and other tissues
  • playing a crucial role in normal bone development
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) OBDL
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS