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FLASH GENE

Symbol

FAM19A4

contributors: - updated : 21-11-2005

HGNC name	family with sequence similarity 19 (chemokine (C-C motif)-like), member A4
HGNC id	21591

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	3p14.1      Physical location : 68.780.916 - 68.981.711
Synonym name	TAFA4 protein
Synonym symbol(s)	TAFA4

DNA

TYPE	functioning gene
STRUCTURE	200.00 kb     6 Exon(s)

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed variant 1 - - 2248 - 140 - Tom Tang a longer 5' UTR compared to transcript variant 2, both variants encode the same protein variant 2 - - 2166 - 140 - Tom Tang using a different donor splice site in the 5' noncoding exon, thus has a shorter 5' UTR compared to transcript variant 1

EXPRESSION

Type

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Nervous brain diencephalon thalamus       brain forebrain cerebral cortex frontal

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

conserved cysteine residues

HOMOLOGY

Homologene

FAMILY

TAFA family

CATEGORY

regulatory , signaling cytokine

SUBCELLULAR LOCALIZATION	extracellular
text	secreted

basic FUNCTION

may function as brain-specific chemokines or neurokines, that act as regulators of immune and nervous cells

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS