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FLASH GENE
Symbol FAM19A3 contributors: - updated : 21-11-2005
HGNC name family with sequence similarity 19 (chemokine (C-C motif)-like), member A3
HGNC id 21590
Location 1p13.2      Physical location : 113.263.188 - 113.269.854
Synonym name TAFA3 protein
Synonym symbol(s) TAFA3
DNA
TYPE functioning gene
STRUCTURE 6.00 kb     5 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 1077 - 133 - Tom Tang
using a different acceptor splice site for one of the coding exons compared to variant 2, resulting in a shorter isoform 1 than isoform 2
- - 1144 - 169 - Tom Tang
encoding the longer isoform
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrainforebraincerebral cortexfrontal 
 brainforebraincerebral cortexparietal 
 brainforebraincerebral cortextemporal 
 brainbasal nuclei   
Visualeyeuveachoroid  
 eyeretina   
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialbarrier/liningretinal pigment epithelium (RPE)  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY FAM19/TAFA family
CATEGORY regulatory , signaling cytokine
SUBCELLULAR LOCALIZATION extracellular
text secreted
basic FUNCTION
  • may function as brain-specific chemokines or neurokines, that act as regulators of immune and nervous cells
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS