Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Orphanet	Ensembl
	HGNC	UniGene	Nucleotide	OMIM		UCSC

Home Page

FLASH GENE

Symbol

FAM134B

contributors: mct/npt - updated : 30-05-2009

HGNC name	family with sequence similarity 134, member B
HGNC id	25964

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Corresponding disease	HSAN2B hereditary sensory and autonomic neuropathy type IIB
Location	5p15.1      Physical location : 16.473.147 - 16.617.118
Synonym name	hypothetical protein LOC54463
Synonym symbol(s)	FLJ20152, FLJ22155 , FLJ22179

DNA

TYPE	functioning gene
STRUCTURE	143.97 kb     9 Exon(s)

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed NM_001034850 9 - 3259 NP_001030022 54 497 - Tang (2007) NM_019000 7 - 3108 NP_061873 - 356 - Tang (2007)

EXPRESSION

Type

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Endocrine parathyroid       highly Nervous nerve         Urinary kidney

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Muscular

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

HOMOLOGY

Homologene

FAMILY

FAM134 family

CATEGORY

protooncogene

SUBCELLULAR LOCALIZATION

basic FUNCTION

has a prominent capacity to transform normal cells and may play a critical role in the molecular pathogenesis of esophageal squamous cell carcinoma (Tang 2007)

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

corresponding disease(s)

HSAN2B

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in esophageal squamous cell carcinoma (Tang 2007)

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS