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FLASH GENE
Symbol FABP6 contributors: - updated : 18-07-2005
HGNC name fatty acid binding protein 6, ileal (gastrotropin)
HGNC id 3561
Location 5q23-q35      Physical location : 159.614.373 - 159.665.729
Synonym name
  • gastrotropin
  • ileal lipid binding protein
  • Synonym symbol(s) ILBP, IL15P, ILBP3, IBABP
    DNA
    TYPE functioning gene
    STRUCTURE 9.00 kb     4 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked   status provisional
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveintestinesmall intestineileum highly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Epithelial    
    Membranemucouslamina propriaintestine villi 
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    repeated structure + topology beta barrel and remarkable structural signature
    HOMOLOGY
    interspecies homolog to murine Fabp6
    Homologene
    FAMILY lipocalin, calycin family
    CATEGORY regulatory , transport carrier
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic
    basic FUNCTION
  • fatty acid binding protein 6, ileal lipid-binding protein, intestinal bile acid binding protein
  • implicated in the enterohepatic circulation of bile acids and, hence, in cholesterol homeostasis
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    Other regulated by NR1H3
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS