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FLASH GENE
Symbol EXOSC5 contributors: - updated : 20-12-2004
HGNC name exosome component 5
HGNC id 24662
Location 19q13.1      Physical location : 41.892.277 - 41.903.256
Synonym name exosome component Rrp46
Synonym symbol(s) p12B, RRP46, RRP41B, Rrp46p, MGC12901
DNA
TYPE functioning gene
STRUCTURE 11.00 kb     6 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivemale systemtestis   
cell lineage
cell lines highly in a variety of hematopoietic and epithelial tumor cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY RNAse PH family
CATEGORY RNA associated
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm
intracellular,nucleus,nucleolus
basic FUNCTION
  • required for the 3'processing of the 7s pre-rna to the mature 5.8s rrna. has a 3'-5' exonuclease activity
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS