basic FUNCTION
| regulating transcription |
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having a role in progression of breast cancer |
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role of adaptor molecule in the interactions of adhesion receptors and intracellular tyrosine kinases |
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is required for spermatogonial stem cell self-renewal |
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pivotal and complementary roles of ETV4 and ETV5 transcription factors in events crucial to mammary tumorigenesis  |
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regulate growth cone and coordinate membrane and actin dynamics in responses to SEMA3A  |
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with ETV4, are key components of a gene network downstream of Ret that promotes and controls renal branching morphogenesis  |
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important factor for the self-renewal of Spermatogonial stem cells (SSCs) and the maintenance of spermatogenesis  |
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directly regulates CXCL12 gene expression by interacting with its cis-acting element in response to FGF2 stimulation in Sertoli cells  |
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plays important roles in development and tumorigenesis  |
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having a direct role on epithelial-to-mesenchymal transition (EMT)  |
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ETV4 and ETV5 are essential molecules of the transcriptional program linking neurotrophin signaling to sensory neuronal differentiation, suggesting that they can be involved in NGF-mediated target innervation |
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is a transcription factor that is required for fertility  |
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physiological role for ETV5 in many aspects of development including embryonic and perinatal survival, postnatal growth, limb patterning, kidney development and fertility  |
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is a signal transducer and activator of transcription 3-induced positive regulator of TH17 development  |
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ETV4 and ETV5, potentially through regulation of GBX2 and TCF15, are involved in the ES cell proliferation and induction of differentiation-associated genes in ES cells  |
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ETV5 and SPI1 function in parallel to promote Th9 cell development  |
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ETV5 is a transcription factor responsible for maintaining the spermatogonial stem cell niche  |
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ETV5 plays a crucial role in regulating IL10 production in Th2 cells by facilitating the binding of IL10-inducing transcription factors at the IL10 locus  |
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ETV5 is a critical output of RAS signaling in alveolar type II (AT2) cells, contributing to both lung homeostasis and tumor initiation  |
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regulates ductal morphogenesis with SOX9 and is critical for regeneration from pancreatitis  |