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FLASH GENE
Symbol ETAA1 contributors: npt - updated : 04-01-2010
HGNC name Ewing tumor-associated antigen 1
HGNC id 24648
Location 2p14      Physical location : 67.624.441 - 67.637.533
Synonym name
  • Ewing's tumour-associated antigen 16
  • ETAA16 protein
  • Synonym symbol(s) ETAA16, FLJ22647
    DNA
    TYPE functioning gene
    STRUCTURE 13.09 kb     6 Exon(s)
    MAPPING cloned Y linked N status confirmed
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    6 - 3298 103.3 926 - -
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestivepharynx   highly
    Lymphoid/Immunelymph node   moderately
    Reproductivefemale systembreastmammary gland predominantly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Connectiveadipose  highly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a coiled coil domain
  • HOMOLOGY
    interspecies homolog to rattus Etaa1 (56.5 pc)
    homolog to murine Etaa1 (55.4 pc)
    Homologene
    FAMILY
    CATEGORY antigen
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • functioning as a tumour-specific cell surface antigen (Borowski 2006)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    Other phosphorylated upon DNA damage, probably by ATM or ATR
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS