Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | ERP29 | contributors: mct - updated : 24-08-2011 |
HGNC name | endoplasmic reticulum protein 29 |
HGNC id | 13799 |
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Location | 12q24.13 Physical location : 112.451.151 - 112.461.024 |
Synonym name | |
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Synonym symbol(s) | ERP28, ERp31, PDI-DB, C12orf8, PDIA9 |
DNA |
TYPE | functioning gene |
STRUCTURE | 9.87 kb 3 Exon(s) |
regulatory sequence | Promoter |
cytosine-phosphate-guanine/HTF | |
text structure | interaction of the predicted GC and E box elements within the core promoter with Sp1/Sp3 and USF1/USF2 transcription factors |
MAPPING | cloned | Y | linked | N | status | provisional |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | ubiquitous |
tissue |
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cells |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES | globular | Hydrophilic | ||
STRUCTURE |
motifs/domains
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mono polymer | dimer |
HOMOLOGY |
interspecies | homolog to rattus Erp29 |
intraspecies | homolog to AGR2, TXNDC12 |
Homologene |
FAMILY | protein disulfide isomerase family |
CATEGORY | chaperone/stress , enzyme , tumor suppressor , transport |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm,organelle,lumen | |
intracellular,cytoplasm,organelle,endoplasmic reticulum |
basic FUNCTION | |
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CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS | cellular trafficking transport |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein | |
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cell & other |
REGULATION |
Other | not responsive to metabolic stress |
ASSOCIATED DISORDERS |
corresponding disease(s) |
Other morbid association(s) |
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Susceptibility |
Variant & Polymorphism
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |
in mice Erp29 may be one of the important factors involved in sperm fertilization by facilitating sperm-oocyte membrane fusion |