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FLASH GENE
Symbol ERI2 contributors: np/ - updated : 26/11/2008
HGNC name ERI1 exoribonuclease family member 2
HGNC id 30541
Location 16p12.3      Physical location : 20.791.515 - 20.817.795
Synonym name
  • exonuclease domain containing 1
  • enhanced RNAi three prime mRNA exonuclease homolog 2 (C.elegans
  • exoribonuclease 2
  • Synonym symbol(s) KIAA1504, MGC16943, EXOD1
    EC.number 3.1.-.-
    DNA
    TYPE functioning gene
    STRUCTURE 26.28 kb     11 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    11 - 1503 37.3 328 - -
    9 - 3529 77.3 691 - -
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Hearing/Equilibriumear   highly
    Lymphoid/Immunelymph node   highly
     tonsils   moderately
    Nervousnerve   highly
    Reproductivefemale systemuteruscervix moderately
     male systemprostate  predominantly
     male systemtestis  moderately
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Blood / hematopoieticbone marrow  highly
    Muscular   moderately
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • an exonuclease domain
  • HOMOLOGY
    Homologene
    FAMILY
  • EXOD1 family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    basic FUNCTION
  • acting as an exonuclease
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
  • Mg2+ (2 ions per subunit)
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS