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FLASH GENE
Symbol ERGIC3 contributors: mct/npt - updated : 30-03-2007
HGNC name ERGIC and golgi 3
HGNC id 15927
Location 20pter-q12      Physical location : 34.129.777 - 34.145.404
Synonym name
  • hypothetical 43.2Kd protein
  • serologically defined breast cancer antigen NY-BR-84
  • chromosome 20 open reading frame 47
  • endoplasmic reticulum-Golgi intermediate compartment protein 3
  • Synonym symbol(s) CGI-54, PRO0989, C20orf47, NY-BR-84, SDBCAG84, Erv46, dJ477O4.2
    DNA
    TYPE functioning gene
    STRUCTURE 15.63 kb     14 Exon(s)
    MAPPING cloned Y linked N status confirmed
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - splicing 1383 43 388 - -
  • 14 exons
  • - splicing 1368 43 383 - Nishikawa
  • 13 exons
  • lacking exon 8
  • EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart   moderately
    Digestiveintestinelarge intestinecolon predominantly
    Endocrineneuroendocrinepituitary  moderately
     thyroid   highly
    Lymphoid/Immunespleen   moderately
    Nervousbrainhindbraincerebellum highly
     brainforebraincerebral cortex highly
     spinal cord   highly
    Reproductivefemale systemovary  highly
     female systembreastmammary gland moderately
     female systemuteruscervix moderately
    Urinarykidney   highly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a potential transmembrane domain
  • conjugated GlycoP
    HOMOLOGY
    interspecies homolog to rattus Ergic3 (98.71 pc)
    homolog to murine Ergic3 (98.17 pc)
    homolog to chicken ERGIC3 (90.86 pc)
    Homologene
    FAMILY
  • ERGIC family
  • CATEGORY transport
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,endoplasmic reticulum
    intracellular,cytoplasm,organelle,Golgi
    text ER-Golgi intermediate compartment
    basic FUNCTION
  • playing a possible role in transport between endoplasmic reticulum and Golgi
  • playing an important role in cell growth (increasing) and endoplasmic reticulum stress-induced cell death (decreasing)
  • CELLULAR PROCESS cell life, proliferation/growth
    cell life, cell death/apoptosis
    PHYSIOLOGICAL PROCESS cellular trafficking transport
    text endoplasmic reticulum to Golgi vesicle-mediated transport
    PATHWAY
    metabolism
    signaling
    a component
  • ERGIC2-ERGIC3 complex involved in transport between the endoplasmic reticulum and Golgi complex
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
  • ERGIC1
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS