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FLASH GENE
Symbol ERAS contributors: - updated : 29-03-2004
HGNC name ES cell expressed Ras
HGNC id 5174
Location Xp11.23      Physical location : 48.687.282 - 48.688.548
Synonym name
  • small GTPase protein E-Ras
  • v-Ha-ras Harvey rat sarcoma viral oncogene homolog 2
  • v-Ha-ras Harvey rat sarcoma viral oncogene homolog pseudogene
    • Synonym symbol(s) HRAS2, HRASP
    DNA
    TYPE functioning gene
    STRUCTURE 1.00 kb     1 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    interspecies homolog to murine Eras
    Homologene
    FAMILY Ras GTPase superfamily
    CATEGORY enzyme , protooncogene
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • constitutively active
  • GTPase activity, important in the tumor-like growth properties of embryonic stem cells
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism energetic
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule nucleotide,
    GTP binding
    protein interacts with PI3 hydroxygenase
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS