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FLASH GENE
Symbol EPYC contributors: np - updated : 10-07-2006
HGNC name epiphycan
HGNC id 3053
Location 12q21.3-q22      Physical location : 91.357.457 - 91.398.803
Synonym name
  • epiphycan proteoglycan
  • dermatan sulfate proteoglycan 3
  • small chondroitin/dermatan sulfate proteoglycan
  • Synonym symbol(s) PGLB, Pg-Lb, SLRR3B, DSPG3
    DNA
    TYPE functioning gene
    STRUCTURE 41.00 kb     7 Exon(s)
    text structure several transcription factor binding sites
    MAPPING cloned Y linked   status confirmed
    Map cen - ATP2B1 - D12S1122 ,D12S365 - D12S316 - D12S82 - D12S1717 - EPYC - D12S1441 /KERA - LUM - DCN - D12S1992 - D12S1046 - D12S351 - D12S322 - D12S7 - BTG1 - qter
    Authors Deere (96), Pellegata (00)
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    7 - 1594 36 322 - -
    EXPRESSION
    Type restricted
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Hearing/Equilibriumear   highly
    Reproductivefemale systemplacenta   
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Connectivebone  highly
    Connectivecartilage   
    Connectivedenseligament  
    cells
    SystemCellPubmedSpeciesStageRna symbol
     chondrocyte
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period pregnancy
    Text placenta
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • ten leucine-rich repeats (LRR)
  • cysteine-rich regions
  • a N linked glycosylation site (NKSIT motifs) in the LRR region, keratan sulfate proteoglycan
  • HOMOLOGY
    Homologene
    FAMILY
  • small leucine-rich proteoglycan (SLPR) family
  • CATEGORY structural protein
    SUBCELLULAR LOCALIZATION extracellular
    text extracellular matrix ECM
    basic FUNCTION
  • putatively involved in protein-protein interactions
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • collagen fibrils and other ECM proteins
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS