Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol EPS15L1 contributors: - updated : 30-11-2004
HGNC name epidermal growth factor receptor pathway substrate 15-like 1
HGNC id 24634
Location 19p13.12      Physical location : 16.472.407 - 16.582.762
Genatlas name epidermal growth factor receptor substrate EPS15R
Synonym symbol(s) EVI90, EPS15R
DNA
TYPE functioning gene
STRUCTURE 110.00 kb     23 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • tropomyosin domain
  • three EH domains
  • one coiled coil region
  • one UIM motif for ubiquitin recognition and monoubiquitination
  • B box C terminal domain
    • HOMOLOGY
    interspecies homolog to murine Eps15r
    Homologene
    FAMILY Ezrin/radixin/noesin family
    CATEGORY adaptor
    SUBCELLULAR LOCALIZATION
    basic FUNCTION adaptator between ubiquitinated membrane cargo and either the clathrin coat or other endocytic scaffold
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS