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FLASH GENE
Symbol EPG5 contributors: mct - updated : 18-04-2011
HGNC name ectopic P-granules autophagy protein 5 homolog (C. elegans)
HGNC id 29331
Location 18q12.3      Physical location : -
Synonym name
  • hypothetical protein LOC57724
  • KIAA1632
  • Synonym symbol(s) HEEW1, DKFZp667P2311, KIAA1632
    DNA
    TYPE functioning gene
    STRUCTURE 119.73 kb     44 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    44 - 12715 - 2579 - 2007 17549423
    EXPRESSION
    Type restricted
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveliver     Homo sapiens
    Lymphoid/Immunethymus     Homo sapiens
    Nervousbraindiencephalonamygdala moderately
    Reproductivemale systemprostate    Homo sapiens
    Respiratorylung     Homo sapiens
    Urinarykidney     Homo sapiens
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Muscularstriatumcardiac   Homo sapiens
    Muscularstriatumskeletal   Homo sapiens
    Nervouscentral    Homo sapiens
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a shared signature motif found in three well-characterized cancer antigens
  • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY antigen
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • potential immunogenic cancer antigen
  • essential for starvation-induced autophagy
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --over  
    in breast and cervical cancer
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS