basic FUNCTION
| phosphodiesterase I, beta nucleotide pyrophosphatase |
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involved in hydrolysis of extracellular nucleotides |
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involved in the infiltration of neoplastic bile duct carcinoma and is possible to be a tumor marker |
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has an extracellular role in modulating nucleotide-mediated signal transduction, a process that is known as purinergic signaling |
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basophil cell surface marker used to diagnose and monitor various allergic diseases |
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marked differences in the signaling requirements for expression of ENPP3 and ITGAM versus CD63 expression and histamine release in human basophils |
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is an inhibitor for MGAT5B, which catalyzes the hydrolysis of the nucleotide sugar donor substrate UDP-GlcNAc |
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important link of ENPP3 to the regulatory system for dictating the level of intracellular nucleotide sugars |
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plays likely a role in the glial cell differentiation process |
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has an intracellular function in which it plays a role in modulating the level of intracellular nucleotide sugars, possibly through its catalytic activity |
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nucleotide-converting ectoenzymes, such as ENTPD1, ENTPD7, and ENPP3, inhibit ATP-dependent immune responses by hydrolyzing ATP, thereby contributing to immune response regulation |
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ATP-hydrolyzing ectoenzymes ENPP3 has a nonnegligible role in the regulation of basophil- and mast cell-mediated allergic responses |