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FLASH GENE
Symbol EML2 contributors: - updated : 03-03-2007
HGNC name echinoderm microtubule associated protein like 2
HGNC id 18035
Location 19q13.32      Physical location : 46.112.659 - 46.148.775
Synonym name echinoderm MT-associaated protein (EMAP)-like protein 70
Synonym symbol(s) ELP70, EMAP2, EMAP-2
DNA
TYPE functioning gene
STRUCTURE 30.00 kb     19 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveesophagus   highly
Endocrineparathyroid   highly
Lymphoid/Immunethymus   highly
Nervousbrain    
Reproductivemale systemprostate   
Respiratoryrespiratory tractlarynx  highly
Urinarykidney    
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period fetal, pregnancy
Text placenta, spleen
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • 11 WD repeats
  • a highly conserved hydrophobic ELP domain
  • HOMOLOGY
    Homologene
    FAMILY EMAP family of WD-repeat proteins
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION extracellular
        plasma membrane
        intracellular
    intracellular,nucleus,chromatin/chromosome
    text mitotic apparatus
    basic FUNCTION
  • may be modifying the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS