Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol EMCN contributors: npt - updated : 11-02-2005
HGNC name endomucin
HGNC id
Location 4q23      Physical location : 101.316.499 - 101.439.250
Synonym name
  • endomucin-2
  • gastric cancer antigen Ga34
  • Synonym symbol(s) EMCN2, MUC14
    DNA
    TYPE functioning gene
    STRUCTURE 120.20 kb     12 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    12 - 1488 27.3 261 - -
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart   highly
    Reproductivefemale systemplacenta   
     female systembreast   
    Respiratorylung   highly
    Urinarykidney   highly
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Blood/Hematopoieticleukocyte
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a N-terminal signal peptide
  • a uteroglobin homology domain
  • a phosphatidylinositol 3-kinase RAS-binding domain
  • several sites for N-glycosylation
  • N-myristoylation and phosphorylation
  • conjugated GlycoP
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY secretory
    SUBCELLULAR LOCALIZATION extracellular
        plasma membrane
    text may have a secreted form
    basic FUNCTION
  • mucin-like sialoglycoprotein that interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS